OBJECTIVE AND OBJECTIVES OF THE PROJECT
Parkinson’s disease is a common neurological disorder due to the progressive loss of dopaminergic and other neurons in a small area of the subcortical brain structures. Patients with Parkinson’s often have impairments in their motor skills. In addition to bent posture, restlessness, stiffness, immobility (or slow motion) and instability, Motor blocks are another common negative feature of the disease. Motor blocks most commonly affect patients’ feet while walking, and are generally referred to as FOG. The World Health Organization estimates that about 10 million people worldwide have Parkinson’s disease. At European level, according to the European Parkinson’s Disease Association (EPDA), about 1% of people over the age of 60 suffer from the disease. However, in 10% of these patients the disease is diagnosed before the age of 50. There is also a juvenile form of the disease that occurs in people under the age of 40 and accounts for 5-10% of all Parkinson’s disease patients. Parkinson’s is just one of many neurodegenerative disorders, estimated to be 2040 more likely to develop in 2040 even in cases of cancer.
The solution we propose in this research proposal aims at four main objectives: